Renal fibroblasts are the exclusive source of extracellular matrix in the kidneys. They are responsible for the synthesis of collagen, fibronectin, and extracellular matrix degrading proteins. These cells are desmin, kidney-specific epithelial cadherin, and e-selectin negative; and are alpha-SMA and fibronectin positive. These cells are an excellent model for studying fibrosis, urinary and kidney diseases, and for establishing 3D constructs of the renal system. Notoriously challenging to isolate and purify, IVD Technologies guarantees high purity and viability of the cells we provide.
Normal adult human kidney derived cells